The Ghudamis route was terminated in 1952, and the Casablanca run was taken over by Air France the same year.
During 1955, the carrier transported 92,344 passengers.
At year end, the number of employees was 140.
In 1957 the Tunisian government became the largest shareholder (51%) and the stake held by Air France was reduced to 15%.
The carrier took delivery of its first jet-powered aircraft, a Sud Caravelle III, on 31 August 1961. A new service to Frankfurt was inaugurated in October but it was terminated in March the following year due to poor economical performance. A second Caravelle was ordered in 1963 and entered service in March 1964. In cooperation with Lufthansa, flights to Frankfurt were restarted in April 1966 using Caravelle equipment. The Nord 262 was first put into service in 1969. The introduction of this aircraft into the fleet along with the airline already having two Caravelles in operation allowed the carrier to phase out a DC-3 and two DC-4s. The number of employees had grown to 888 by March 1970. At this time, they had four Caravelles, two Cessna 402s, a DC-3 and a Nord 262, which were used on domestic services and international routes to Algeria, Belgium, France, Germany, the Netherlands, Italy, Libya, Morocco and Switzerland. Tunis Air took delivery of its first Boeing aircraft, a Boeing 727-200, on 12 March 1972; it was put on service on the Tunis–Paris run. On 1 April 1972, a Boeing 707 that was leased from Sabena inaugurated the Tunis–London link. The same day, new services to Luxembourg and Jeddah were launched. Late in the year, a second Boeing 727s was ordered for delivery in July 1973. In 1973, a third Boeing 727 was ordered for handover in 12 that year. A fourth and fifth 727 were ordered in 1974 and 1975. The gradual incorporation of the Boeing 727s permitted Tunisair to replace the Caravelles and to retire the remaining DC-3s.
For the first time in its history, in 1995 the carrier started trading its shares at the Tunis stock exchange when 20% of the stake was floated. Ahmed Smaoui took over as president and director general of the company in March 1997. In January 1999, Abdelmalek Larif became the new president. Also in 1999, flights to Amman and Beirut were launched. By April 2000 the airline had employees. At this time the fleet comprised one Airbus A300B4-200, two Airbus A319-100s, ten Airbus A320-200s, four Boeing 727-200 Advanced, three Boeing 737-200 Advanced, four Boeing 737-500s and three Boeing 737-600s that served the following destinations: Abu Dhabi, Algiers, Amman, Amsterdam, Athens, Barcelona, Beirut, Berlin, Bilbao, Bordeaux, Bratislava, Brussels, Budapest, Cairo, Casablanca, Copenhagen, Dakar, Damascus, Djerba, Düsseldorf, Frankfurt, Gafsa, Geneva, Graz, Hamburg, Istanbul, Jeddah, Lille, Linz, Lisbon, London, Luxembourg, Lyon, Madrid, Malta, Marseille, Milan, Monastir, Munich, Nice, Nouakchott, Palermo, Paris, Prague, Rome, Salzburg, Sfax, Stockholm, Strasbourg, Tabarka, Toulouse, Tozeur, Tunis, Vienna, Warsaw and Zurich.
In 2007, Nabil Chettaoui was appointed as chief executive officer (CEO). In June 2011, Hamadi Thamri replaced Chettaoui as president and CEO of the company. In July the same year, Moscow was first served by the carrier with flights to Domodedovo Airport. The airline's first transatlantic service, Tunis–Montreal, was launched in July 2016.
