Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsværd.[3] Novo Nordisk is controlled by majority shareholder Novo Holdings A/S (wholly owned by the Novo Nordisk Foundation) which holds approximately 28.1% of its shares and a majority (77.1%) of its voting shares.[4]
Novo Nordisk manufactures and markets pharmaceutical products and services, specifically diabetes and obesity medications and devices.[5]
Novo Nordisk employs more than 48,000 people globally, and markets its products in 168 countries.[6] The corporation was created in 1989, through a merger of two Danish companies, which date back to the 1920s. Novo Nordisk is a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA).[7]
The company was ranked 25th among Fortune's 100 Best Companies to Work For in 2010, and subsequently ranked 72nd in 2014 and 73rd in 2017.[8][9][10] In January 2012, Novo Nordisk was named the most sustainable company in the world by the business magazine Corporate Knights, while spin-off company Novozymes was named fourth.[11] It is a leader in the FTSE4Good Index, and the only European company in the top ten.[12] Novo Nordisk is the largest pharmaceutical company in Denmark.[13] Novo Nordisk's market capitalization exceeded the GDP of Denmark's domestic economy in 2023, and it is the highest valued company in Europe.[14]
History
1922-1925
In 1922, August Krogh, a professor at the University of Copenhagen, went on a lecture tour to North America after receiving the Nobel Prize in Physiology or Medicine. During this tour, Krogh and his wife Marie visited Toronto where the scientists Frederick Banting, Charles Best and John Macleod had just succeeded in manufacturing active insulin. Krogh received permission to manufacture insulin in the Nordic countries and joined forces with Hans Christian Hagedorn, a physician specialising in diabetes, to start the production of insulin in Denmark. This led to the establishment of Nordisk Insulinlaboratorium company in 1923.[15]
In 1925, brothers Harald and Thorvald Pedersen, who were former employees of Nordisk, formed their own company, Novo Terapeutisk Laboratorium. Novo and Nordisk competed until they merged in 1989 to become Novo Nordisk A/S.[16]
1982–1994
Products
Novo Nordisk makes the drug semaglutide, used to treat diabetes under the brand names Ozempic and Rybelsus and obesity under the brand name Wegovy.[58] Novo Nordisk is also involved with hemostasis management, growth hormone therapy, and hormone replacement therapy. The company makes several drugs under various brand names, including Levemir, Tresiba, NovoLog, Novolin R, NovoSeven, NovoEight, and Victoza.[1]
Toxicogenomics
Novo Nordisk is involved in government funded collaborative research projects with other industrial and governmental partners. One example in the area of non-clinical safety assessment is the InnoMed PredTox.[59][60] The company is expanding its activities in joint research projects within the framework of the Innovative Medicines Initiative of European Federation of Pharmaceutical Industries and Associations and the European Commission.[61]
Research and pipeline
In 2025, Novo Nordisk tested whether semaglutide helped slow progression for Alzheimer’s disease. However, on Nov. 24, 2025, the company announced that the studies failed to find any effect of the drug on cognition and functioning in people with mild cognitive impairment or with dementia.[62]
Novo Nordisk was researching pulmonary delivery systems for diabetic medications, and in the early stages of research into autoimmune and chronic inflammatory diseases, using technologies such as translational immunology and monoclonal antibodies.[63] In September 2014, the company announced a decision to discontinue all research in inflammatory disorders, including the discontinuation of R&D in anti-IL-20 for the treatment of rheumatoid arthritis.[64]
In September 2018, it was reported that the company would lay off 400 administrative staff, laboratory technicians and scientists, in Denmark and China in order to concentrate research and development efforts on “transformational biological and technological innovation”.[65]
Controversies
In 2010, Novo Nordisk breached the code of conduct for Association of the British Pharmaceutical Industry (ABPI), by failing to provide information about side-effects of Victoza and by promoting Victoza prior to being granted market authorisation.[66]
In 2013, Novo Nordisk had to pay back dkk3.6billion to the Danish tax authorities due to transfer mispricing.[67]
In March 2013, a debate emerged in which scientists questioned whether the incretin class of diabetic medications – the class to which Victoza belongs – had an increased risk of side effects in the pancreas such as pancreatitis and pancreatic cancer. It was concluded that data currently available did not confirm these concerns.[68]
In October 2013, batches of NovoMix 30 FlexPen and Penfill insulin were recalled in some European countries as their analysis had shown that a small percentage of the products in these batches did not meet the specifications for insulin strength.[69]
Corporate affairs
Finances
For the fiscal year 2024, Novo Nordisk reported earnings of DKK 101 billion (around 14.5 billion USD), with an annual revenue of DKK 290.4 billion (around 42.1 billion USD), an increase of 25% over the previous fiscal cycle.[84][85]
Ownership
Novo Nordisk shares are mostly owned by institutional investors and Novo Holdings A/S. The largest shareholders in 2025 were:[86]
- Novo Holdings A/S (28.1%)
See also
- Captain Novolin
- NNIT (formerly Novo Nordisk IT)
- Novo Nordisk Foundation
- Novo Nordisk Foundation Center for Protein Research
- Repaglinide
- Team Novo Nordisk
External links
References
- Annual Report 2024 Novo Nordisk, retrieved February 5, 2025^
- Financial report for the period 1 January 2025 to 31 December 2025 Novo Nordisk, February 3, 2026^
- Who we are www.novonordisk.com, retrieved 2021-09-28