List of seasonal influenza vaccines

Seasonal influenza vaccine brands include Fluzone/Fluzone Quadrivalent and Vaxigrip/VaxigripTetra, Influvac and Optaflu.

AstraZeneca

Fluenz, Flumist and their quadrivalent formulations are nasal attenuated vaccines by AstraZeneca.

• Fluenz[1]
• Fluenz Tetra[2]
• Flumist[3]
• Flumist Quadrivalent[4]

GlaxoSmithKline

Fluarix, Flulaval and their quadrivalent formulations are split virus inactivated vaccines by GlaxoSmithKline.[5]

• Fluarix
• Flulaval
• Fluarix Tetra

Mylan/Viatris

Influvac and its quadrivalent formulation are surface antigen subunit vaccines marketed by Mylan.

They contain inactivated purified surface fragments (subunits) from the three different strains of the influenza virus (A/H1N1, A/H3N2, and Influenza B virus) that are selected and distributed by the World Health Organization, on the basis of their latest recommendations. Previously, they were produced and marketed by Abbott Laboratories

In February 2010, Abbott acquired the vaccines subunit from Solvay Pharmaceuticals included in its $6.2 billion purchase and the subunit influenza vaccine — Influvac has been commercially available on the market since the early nineteen-eighties. With the acquisition of Solvay, Abbott retained access to the Eastern European, Middle Eastern & Latin American markets. Approximately $850 million of sales revenue from vaccines was reported by Solvay Pharmaceuticals in 2009.

In February 2015, Mylan Laboratories completed the deal with Abbott to purchase Abbott's generic drugs business in developed markets, which includes Influvac.[6][7]

Novartis

In April 2007, Novartis received a positive opinion supporting European Union approval of Optaflu. In 2014, Novartis' flu vaccine unit was sold to CSL Limited, and placed under CSL subsidiary, bioCSL (Seqirus) as marketing authorization holder.[10] In 2017, bioCSL decided to discontinue the usage of the Optaflu brand for commercial reasons.[11][12]

• Optaflu was a trivalent surface antigen inactivated vaccine, the first flu vaccine made in mammalian cell cultures rather than chicken eggs, manufactured by Novartis.

Sanofi-Aventis

Vaxigrip Tetra and Fluquadri are quadrivalent split virus inactivated vaccines by Sanofi-Aventis.

• Vaxigrip Tetra[13]
• Fluquadri[13]

Sanofi Pasteur

Sanofi Pasteur produces the following vaccines:

• Fluzone
• Vaxigrip/Vaxigrip Tetra
• Flublok[14]

• Supemtek/Supemtek Tetra

Seqirus

Afluria and its quadrivalent formulation are a split virus inactivated vaccines. Fluad and its quadrivalent formulations are adjuvanted surface antigen inactivated vaccines. Flucelvax and its quadrivalent formulations are surface antigen inactivated vaccines prepared in cell cultures.

Novartis developed the first influenza vaccine, which did not need to be grown in chicken eggs, a cell-based vaccine.[25] In 2014, CSL Limited obtained Novartis' flu vaccine unit, and transferred it to CSL Subsidiary, bioCSL, named Seqirus.[10]

The following are list of bioCSL flu vaccine brands:[26]

• Trivalent

See also

• H5N1 vaccine
• Historical annual reformulations of the influenza vaccine
• Pandemrix, a historic H1N1 pandemic flu vaccine

External links