Array BioPharma

Array BioPharma is an American clinical stage, pharmaceutical company that focuses on oncology medication headquartered in Boulder, Colorado. The company is currently a subsidiary of Pfizer after being acquired for $11 billion in 2019.

History

In 1998, the company was founded by Drs. Tony Piscopio, Kevin Koch, David Snitman, and K.C. Nicolaou.[1]

In November 2000, the company became a public company via an initial public offering.[2]

In June 2019, Pfizer acquired the company for approximately $11 billion.[3]

Discovery of FDA Approved Small Molecules

  • MEKTOVI (Binimetinib) - selective MEK inhibitor - Approved 2018, acquired by Pfizer
  • TUKYSA (Tucatinib) - HER2 inhibitor - Approved 2020, owned by Seagen (Seattle Genetics)
  • BRAFTOVI (Encorafenib) - BRAF inhibitor - Approved 2018, acquired by Pfizer
  • KRAZATI (Adagrasib) - KRasG12C mutation inhibitor - Approved 2022, collaboration with Mirati Therapeutics
  • KOSELUGO (Selumetinib) - MEK1/2 inhibitor - Approved 2020, licensed by Astrazeneca
  • VITRAKVI (Larotrectinib) - TRK Inhibitor - Approved 2018, licensed by Loxo Oncology (Eli Lilly)
  • RETEVMO (Selpercatinib) - RET inhibitor - Approved 2024, licensed by Loxo Oncology (Eli Lilly)
  • GANOVO (Danoprevir) - HCV Protease inhibitor - Approved 2018 (in China), licensed by Roche

References

  1. Co-Founder Of Array BioPharma, Inc. To Lead New Korean Out-Sourcing Chemistry Company BioSpace, retrieved 2020-07-28^
  2. Array IPO up 17% CNN, November 17, 2000^
  3. Pfizer acquires Array BioPharma, valued at $11.4 billion Rappler, 18 June 2019, retrieved 2020-07-29^