Mirati Therapeutics

Mirati Therapeutics, Inc. is an American targeted oncology company that focuses on the development of cancer therapeutics.[1] Bristol Myers Squibb acquired the company in January 2024.

History

Mirati Therapeutics works largely in KRAS-mutation inhibition, and developing treatments for tumors that contain it.[2] The inhibition to the mutation has shown to shrink the size of its tumors.[3] The company is based in San Diego, California. The company’s name comes from the Italian word for “targeted” (Mirati). Mirati Therapeutics is traded on the Nasdaq[4] under the ticker symbol MRTX.[5] It joined the exchange in 2013.[6]

In October 2023, Bristol Myers Squibb agreed to acquire the company in an all-cash deal worth $4.8 billion, and an additional $1 billion in milestone payment.[7] The acquisition was completed in January 2024.[8]

Drug candidates

The company’s leading drug candidates are sitravatinib and adagrasib.[9] Mirati also has a preclinical candidate against the G12D mutation.[10]

Management

The company’s CEO and President is David Meek.[11]

References

  1. Hedge Fund Pick Mirati Rallies to Record After Drug Results BloombergQuint, 25 October 2020^
  2. Mirati Therapeutics: Paying $220 A Share Sounds Excessive But Cracking KRAS Is A Big Deal (NASDAQ:MRTX) Seeking Alpha, 1 January 2021^
  3. Mirati drug shrinks tumors in some cancer patients in early-stage trial CNBC, October 28, 2019^
  4. Why Mirati Therapeutics Stock Is Taking Off Today The Motley Fool, 26 October 2020^
  5. BNK Invest. RSI Alert: Mirati Therapeutics (MRTX) Now Oversold NASDAQ, 29 March 2021^
  6. Mirati Therapeutics Raises $234.3M in Public Stock Offering San Diego Business Journal, 7 July 2021^
  7. Stuart Condie. Bristol Myers Squibb to Acquire Mirati Therapeutics in Deal Worth Up to $5.8 Billion The Wall Street Journal, 8 October 2023^
  8. Bristol Myers Squibb concludes Mirati acquisition for $5.8bn Pharmaceutical Technology, Verdict Media, 24 January 2024^
  9. Mirati Therapeutics: A Gift That Keeps On Giving (NASDAQ:MRTX) Seeking Alpha, 31 December 2020^
  10. How a KRAS program transformed Mirati's story BioCentury, 26 October 2019^
  11. Mirati Therapeutics Appoints David Meek as Chief Executive Officer 20 September 2021^