Pliva

Pliva d.o.o. is a pharmaceutical company based in Zagreb, Croatia that primarily manufactures and sells generic drugs. It is a subsidiary of Teva Pharmaceuticals.

Pliva is one of the world's largest producers of generic Adderall.

History

In 1918 Gustav Janeček founded the wholesale drug company Isis (today Medika).[2] In 1921 he co-founded the pharmaceutical factory Kaštel d.d. in Karlovac as a joint venture with Isis and Budapest-based Chinoin, and served as the company's first president of the board. The company kept its name after moving production to Zagreb in 1927. It was only in 1941 that it was renamed PLIVA as an acronym for the State Institute for Production of Medicines and Vaccines.[3][4][5][6]

A team of Pliva's researchers, Gabrijela Kobrehel, Gorjana Radobolja-Lazarevski and Zrinka Tamburašev led by Dr. Slobodan Đokić, discovered azithromycin in 1980.[7]

In June 2002, the company acquired Sidmak for $152.9 million.[8]

Also in June 2002, Zeljko Peric, the chief financial officer of the company, resigned.[9]

In May 2004, the company received approval from the Food and Drug Administration to sell trospium chloride.[10]

In June 2005, the company received approval to sell a generic version of erythropoietin in Croatia.[11]

In November 2005, the company received approval from the Food and Drug Administration to sell a generic version of Azithromycin,[12] Citalopram,[13] and Ondansetron.[14]

In October 2006, Barr Pharmaceuticals acquired Pliva.[15]

On December 23, 2008, Barr Pharmaceuticals was acquired by Teva Pharmaceuticals and the company became part of Teva Active Pharmaceutical Ingredients (TAPI).[16]

References

  1. Company Profile Pliva^
  2. JANEČEK, Gustav Hrvatski biografski leksikon, retrieved 27 September 2025^
  3. Snježana Bičak. Preteča Plive osnovana je u starom dvorcu u Karlovcu 1921. Večernji list, 1 October 2018, retrieved 27 September 2025^
  4. S. Inić. Adolf Thierry and the first pharmaceutical factory in Croatia Pharmazie, 2021, retrieved 27 September 2025^
  5. PLIVA d.d. International Directory of Company Histories via Encyclopedia.com, retrieved 27 September 2025^
  6. Dionice tvrtke Kaštel, iz koje je kasnije nastala Pliva, oduzete su njegovom djedu krajem 2. svjetskog rata... Jutarnji list, 11 May 2017, retrieved 27 September 2025^
  7. Stjepan Mutak. Azalides from Azithromycin to New Azalide Derivatives The Journal of Antibiotics, 2007^
  8. PLIVA announces acquisition of US-based Sidmak Pliva, June 11, 2002^
  9. PLIVA announces management changes Pliva, June 27, 2002^
  10. PLIVA Announces FDA Approval of SANCTURA Pliva, May 31, 2004^
  11. PLIVA Registers generic EPO in Croatia Pliva, June 21, 2005^
  12. PLIVA Announces Approval for Azithromycin Tablets Pliva, November 15, 2005^
  13. PLIVA Announces Approval for Citalopram Hydrobromide Tablets Pliva, November 3, 2005^
  14. PLIVA Announces Approval for Ondansetron Hydrochloride ODT Pliva, November 21, 2005^
  15. Barr Acquires PLIVA d.d. Pliva, October 12, 2006^
  16. TEVA COMPLETES ACQUISITION OF BARR Pliva, December 23, 2008^