One Manhattan West is a 67-story office skyscraper at 395 Ninth Avenue in the Manhattan West development on the West Side of Manhattan in New York City, United States. Designed by Skidmore, Owings & Merrill (SOM), it was completed in 2019 and is the second tower to be completed in the development after 3 Manhattan West. The tower is rectangular in plan, with a curtain wall that contains insulated glazing, as well as a reinforced-concrete mechanical core. Because One Manhattan West partially overhangs a set of railroad tracks, the mechanical core carries most of the building's structural loads.
One Manhattan West was built as part of the Manhattan West development, for which Brookfield Asset Management began acquiring land in the 1980s. Work on the building started in April 2015, after law firm Skadden, Arps, Slate, Meagher & Flom agreed to become the building's anchor tenant. One Manhattan West officially opened on October 30, 2019. As of 2022, a joint venture of Brookfield, the Qatar Investment Authority, and the Blackstone Group owns the building.