Pre-show
During the No Mercy Kickoff pre-show, Curt Hawkins made his WWE return. As advertised, he stepped into the ring. However, he did not compete, but announced that his first match would take place on the following episode of SmackDown.
After this, Shane McMahon and Daniel Bryan informed Alexa Bliss that for medical reasons, SmackDown Women's Champion Becky Lynch would not be able to compete, that the scheduled title match would be postponed to the November 8 episode of SmackDown, and that Bliss would face a different opponent later in the night.[16]
Also during the pre-show, The Hype Bros (Mojo Rawley and Zack Ryder) and American Alpha (Chad Gable and Jason Jordan) faced The Ascension (Konnor and Viktor) and The Vaudevillains (Simon Gotch and Aiden English). In the end, Jordan performed Grand Amplitude on English to win the match.
Main show
The actual pay-per-view opened with the advertised main event, which was the triple threat match in which AJ Styles defended the WWE World Championship against Dean Ambrose and John Cena. During the match, Cena executed an "Attitude Adjustment" on Ambrose for a near-fall. Cena applied the "STF" on Ambrose, who did not submit. Styles performed a "Springboard 450 Splash" on Ambrose for a near-fall. Styles executed a "Styles Clash" on Ambrose, which was followed by Cena applying the "STF" on Styles, but Ambrose broke the hold. Later, Ambrose applied the "Calf Crusher" and Cena applied the "STF" on Styles simultaneously; Styles submitted, but the referee continued the match as two participants cannot submit another one at the same time. Ambrose executed "Dirty Deeds" on Cena, but Styles voided the pinfall by pulling the referee out of the ring. In the end, after Cena executed a Super "Attitude Adjustment" on Ambrose, Styles attacked Cena with a chair immediately and pinned him to retain the title.
Next, Nikki Bella faced Carmella. The end came when Nikki executed a "Rack Attack 2.0" on Carmella to win the match.
After that, Heath Slater and Rhyno defended the SmackDown Tag Team Championship against The Usos (Jey and Jimmy Uso). The match ended when Rhyno executed a "Gore" on Jey to retain the titles.
In the fourth match, Jack Swagger faced Baron Corbin. In the end, Swagger applied the "Patriot Lock" on Corbin, but Corbin reached the ring apron, forcing Swagger to break the hold, and poked Swagger's eye. Corbin performed the "End of Days" on Swagger to win the match.
Next, Dolph Ziggler challenged The Miz for the Intercontinental Championship in a title vs. career match. During the match, Miz applied the "Figure Four Leglock", but Ziggler touched the ropes, forcing Miz to break the hold. Ziggler executed a "Zig Zag" on Miz for a near-fall. After Maryse blinded Ziggler with pepper spray, Miz executed a "Skull Crushing Finale", but Ziggler placed his foot on the bottom rope to void the pinfall. The Spirit Squad (Mikey and Kenny) appeared to distract Ziggler, but Ziggler knocked Mikey off the ring apron with a Superkick. Miz performed another "Skull Crushing Finale" on Ziggler for a near-fall. The referee ejected Maryse, Mikey, and Kenny from ringside. Ziggler executed a Superkick on Miz to win the title and save his career.
After that, Alexa Bliss came out. Earlier in the night, SmackDown Women's Champion Becky Lynch had been declared unable to compete. Bliss complained about her title opportunity being postponed only for her replacement opponent, Naomi, to interrupt her. In the end, Bliss attempted a Cross Armbar, but Naomi shifted her weight to pin Bliss and win the match.
In the final match, Randy Orton fought Bray Wyatt. During the match, Orton attempted an "RKO" on Wyatt, but Wyatt countered by throwing Orton over the broadcast table. Wyatt attempted "Sister Abigail" on Orton, but Orton countered with an "RKO" attempt, only for Wyatt to counter into a Uranage Slam for a near-fall. Outside the ring, Wyatt draped Orton over the steel steps and attempted a Running Senton, but Orton rolled off and Wyatt crashed onto the steps. In the climax, Orton executed an Elevated DDT on Wyatt and attempted an "RKO", but the lights went out and a returning Luke Harper appeared in the ring, distracting Orton. Wyatt executed "Sister Abigail" on Orton to win the match.