Ironwood Pharmaceuticals, Inc. is a publicly traded pharmaceutical company. It was originally called Microbia, Inc.
Microbia was founded by postdocs from the lab of Gerald Fink at the Whitehead Institute to commercialize approaches that had been developed in the lab to improve industrial fermentation of fungi, to genetically engineer them to produce secondary metabolites more efficiently or to produce new ones as leads for drug discovery or as products for use in industry, and to identify drug targets in fungi for antifungal drug discovery.[1][2] In 2002 the company hired John Talley to lead their antifungal drug discovery efforts,[3] which at the time were focused on identifying small molecules that could inhibit fungal invasins,[3][4] along with Mark Currie who had also worked at