Insulin lispro

verifiedfields	changed
verifiedrevid	458271570
tradename	Humalog, Liprolog, Admelog, others
medlineplus	a697021
dailymedid	Insulin lispro
pregnancy au	A
pregnancy au comment	‡R1R‡
routes of administration	Subcutaneous
atc prefix	A10
atc suffix	AB04
legal ca	Rx-only
legal ca comment	/ Schedule D
legal uk	POM
legal uk comment	‡R2R‡
legal us	Rx-only
legal eu	Rx-only
legal eu comment	,
legal status	Rx-only
onset	30 minutes
duration of action	5 hours
cas number	133107-64-9
pubchem	16132438
drugbank	DB00046
chemspiderid	none
unii	GFX7QIS1II
kegg	D04477
synonyms	URLi, LY900014, LY-275585, insulin lispro-aabc
c	257
h	383
n	65
o	77
s	6
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stdinchikey	WNRQPCUGRUFHED-DETKDSODSA-N

Insulin lispro, sold under the brand name Humalog among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. It is delivered subcutaneously either by injection or from an insulin pump.[3] Onset of effects typically occurs within 30 minutes and lasts about 5 hours. Often a longer-acting insulin like insulin NPH is also needed.

Common side effects include low blood sugar. Other serious side effects may include low blood potassium. Use in pregnancy and breastfeeding is generally safe.[4] It works the same as human insulin by increasing the amount of glucose that tissues take in and decreasing the amount of glucose made by the liver.[5]

Insulin lispro was first approved for use in the United States in 1996.[5]

Insulin lispro

Medical uses

Side effects

Mechanism of action

Chemistry

History

Society and culture

Economics

References