Farmitalia was an Italian pharmaceutical company best known for its parallel discovery with Rhone-Poulenc of daunorubicin and subsequent discovery of doxorubicin.[1] Farmitalia had been founded in 1935 as a joint venture by Rhone-Poulenc and Montecatini. Farmitalia occupied a position of choice in the world rankings of the profession, not only in Italy, but also at the world level with in particular the patent of Adriamycin, an anti-cancer drug qualified. From its creation, Farmaceutici Italia buys the Schiapparelli factory.[2]
In 1978, Farmitalia was merged with Carlo Erba SpA, an Italian pharmaceutical company that had been founded in 1853 by the pharmacist Carlo Erba, in which Montecatini had acquired a controlling interest in 1971. The merged company was called Farmitalia Carlo Erba SpA.[3]
Farmitalia Carlo Erba was acquired by Pharmacia in 1993,[4] then Pharmacia was acquired by Pfizer in 2003.[5]
Drugs discovered at Farmitalia that reached the market included (with date of first publication):
- 1960 Sulfalene[6][7]
- 1963 Daunorubicin[8][9]
- 1969 Doxorubicin[1][10]
- 1980 Cabergoline[11][12]
- 1984 Reboxetine[13][14]
References
- Weiss RB. The anthracyclines: will we ever find a better doxorubicin? Seminars in Oncology, December 1992^
- SETTIMO. La Farmitalia, storia di un'industria Giornale La Voce, 2019-04-17, retrieved 2022-07-25^
- Antonella Bilotto. Carlo Erba SpA LombardiaBeniCulturali, retrieved 9 May 2017^
- Staff. News: Farmitalia bought by Kabi Pharmacia. Ann Oncol (1993) 4 (5): 345.^
- Staff, CNN/Money. April 16, 2003 It's official: Pfizer buys Pharmacia^
- G Baruffa. Clinical trials in Plasmodium falciparum malaria with a long-acting sulphonamide Trans R Soc Trop Med Hyg, 1966^
- Per prior citation, the first publication: B Camerino, G Palamidessi. Derivati della parazina II. Sulfonamdopir (in Italian) Gazz Chim Ital, 1960^
- A Suarato, F Angelucci, C Geroni. Ring-B modified anthracyclines Curr Pharm Des, Mar 1999^
- Grein A, et al. Descrizione e classificazione di un attinomicete (Streptonryces peucetius sp. nova) produttore di una sostanza ad attivita antitumorale. Giorn. Microbiol. 11: 109~ 118, 1963^
- Adriamycin, 14-hydroxydaunomycin, a new antitumor antibiotic from S. peucetius var. caesius Biotechnol Bioeng, 1969^
- Council regulation (EEC) no 1768/92 in the matter of Application No SPC/GB94/012 for a Supplementary Protection Certificate in the name of Farmitalia Carlo Erba S. r. l.^
- Espace record: GB 202074566 retrieved 2016-04-17^
- G Cocchiara. Comparison of the disposition and of the metabolic pattern of Reboxetine, a new antidepressant, in the rat, dog, monkey and man Eur J Drug Metab Pharmacokinet, 1991^
- First publication per prior citation: M Melloni. Potential antidepressant agents. α-aryloxy-benzyl derivatives of ethanolamine and morpholine Eur J Med Chem, 1984^