2002 anime
A Satan cult, whose leaders are demons in human form, begin to hold a series of Black Masses in hopes of reviving an ancient demon known as Dante. Ryo Utsugi, a high school student, begins experiencing strange nightmares and premonitions. Soon after, Ryo's sister, Saori, is kidnapped by these cultists for use in one of their sacrificial ceremonies. Ryo's premonitions guide him to the ritual and he saves her right before it is disrupted by a group of militant Christians. Believing that Ryo's new-found powers could awaken Dante, the cultists orchestrate a chain of events to lead Ryo to the mountains, where he discovers a portal that takes him into the deepest parts of the Himalayas, the heart of Dante's prison.
Using telekinetic powers, Dante uses Ryo to free himself from his ice prison before eating him alive. Meanwhile, the cultists capture an unnamed princess and kill her by successfully performing the Black Mass used to summon Dante for the second and final time, though her body was not found anywhere. However, Dante's consciousness has been taken over by Ryo who, upon seeing his new form, is blinded by rage and rampages through Nagoya. His frenzy ends upon encountering Zenon, an old friend of Dante, who, becoming enslaved by God, was forced to fight and thereby be killed by Dante. Eventually, Ryo encounters the leader of the cultists, who tells him that his birth family was killed in a car accident and his adopted father, who is both a doctor and the leader of a rival cult dedicated to God, was the one who saved him, revealing Saori to be unrelated by blood. In retaliation to Dante's release, the followers of God unleash the Four Devil Kings (悪魔四天王), who wreak havoc on the city by draining the life force of its inhabitants in order to gain Dante's attention. Ryo also meets the demon Medusa, who assumes the form of a supermodel named Saeko Kodai (古代 冴子).
As the story progresses, it is revealed that Ryo is a reincarnation of Dante when he was human. It turned out that Sodom and Gomorrah were a futuristic utopia under the rule of Satan. However, God, an energy-based being, came to Earth and demanded to use the people of Sodom as hosts for its power. When Satan and the people refuse to comply, God proceeds to use animals as vessels to destroy Sodom, an action that resulted in many of its occupants turned into their current demonic forms from being exposed to the residual energies. The survivors of Gomorrah, the last actual humans in existence, became the Satanists who allied themselves with the demons to fight God who took residence in apes and jump-started their evolution into the current human race. Near the end of the conflict that followed, as Satan both sealed himself within another dimension, Dante transferred his human body and soul to Judas Iscariot and Ryo Utsugi respectively to keep fighting after he was sealed. With Ryo finally regaining his memories as Dante while in Sodom and Gomorrah, he teams up with the cultists and plans to finally take vengeance upon God for his sins while releasing Satan.
However, God decides to jumpstart the Apocalypse, gathering the pieces of itself within humans to reform, as the humans ultimately destroy themselves, while taking Saori to make her the ultimate weapon under his control to smite all the demons. After Dante/Ryo succeeds in destroying the first form which was a large serpent featuring Adam and Eve, she transforms into an angelic knight with Saori's body placed in its forehead. She battles Ryo fiercely before managing to break God's hold over her. They then reunite as Adam and Eve, their embrace destroying the world and scattering God back into space to find another world to repeat the cycle of conflict among its native lifeforms. Afterwards, the anime ends with its final scene which shows them holding hands and walking in a prehistoric version of the Garden of Eden.
