Cipla Limited is an Indian multinational pharmaceutical company headquartered in Mumbai. Cipla primarily focuses on developing medication to treat respiratory disease, cardiovascular disease, arthritis, diabetes, depression, paediatric and various other medical conditions. Cipla has 47 manufacturing locations across the world and sells its products in 86 countries. It is the third-largest drug producer in India.[4][5]
History
After meeting Mahatma Gandhi in the early 1920s, Khwaja Abdul Hamied decided to contribute to the Swadeshi movement by pursuing a doctorate in chemistry. In 1935, Hamied founded Cipla as the Chemical, Industrial & Pharmaceutical Laboratories in Mumbai.[6][7] During World War II, the company became the largest supplier of quinine and Vitamin B12 for Allied soldiers.[8] The company name shortened to its current form in July 1984.[7] Upon Hamied's death in 1972, his son Yusuf Hamied, a Cambridge-educated chemist, took over the company.[8]
In 1995, Cipla launched Deferiprone, the world's first oral iron chelator.[6] In 1999, Cipla joined the Indian Pharmaceutical Alliance as a founding member in an effort to promote the development of generic drugs in India.[9][10] During the AIDS epidemic in the early 2000s, Hamied reverse-engineered a three-drug antiretroviral medication that was sold for about $12,000 per year to create a cheaper version that sold for $304 per year.[11] This drug was sold to African charities and governments. It is estimated that "at one time, as much as 40 percent of the AIDS patients in poor countries took Cipla drugs".[11]
During the avian flu pandemic in 2006, Cipla was able to reverse-engineer the drug Tamiflu and sell it for significantly lower prices.[9] In 2013, Cipla acquired the South African company Cipla-Medpro. Its name was changed to Cipla Medpro South Africa Limited and was kept as a subsidiary.[12][13] At the time of the acquisition, Cipla-Medpro had been a distribution partner for Cipla and was South Africa's third-biggest pharmaceutical company.[12] The company had been founded in 2002 under the name Enaleni Pharmaceuticals Ltd.[14] In 2005, Enaleni bought all the shares of Cipla-Medpro, which had been a joint venture between Cipla and Medpro Pharmaceuticals, a South African generics company;[15] in 2008, it changed its name to Cipla-Medpro.[16] In September 2023, it was announced Cipla South Africa had acquired the Midrand-headquartered healthcare products manufacturer, Actor Pharma.[17]
In September 2015, Cipla acquired InvaGen Pharmaceuticals and Exelan Pharmaceuticals, two American pharmaceutical companies, for 555 million dollars.[18] In 2019, Cipla entered digital therapeutics by partnering with Wellthy Therapeutics in India and Brandmed in South Africa.[19] In April 2024, Cipla acquired Ivia Beaute Pvt Ltd's cosmetics and personal care distribution and marketing business for ₹130 crore.[20]
Products and services
Cipla sells active pharmaceutical ingredients to other manufacturers as well as pharmaceutical and personal care products,[21] including the anti-depressant escitalopram oxalate, lamivudine, and fluticasone propionate.[22] Cipla is the world's largest manufacturer of antiretroviral drugs.[21][23]
In July 2020, the company announced the introduction of Gilead Sciences' Remdesivir under the brand name CIPREMI in India after reaching a voluntary licensing agreement with the parent company and DCGI approval for "restricted emergency use" in COVID-19 treatment of patients in critical condition.[24][25][26]
Operations
Cipla has 34 manufacturing units in 8 locations across India and a presence in over 80 countries.[27][28] Exports accounted for 48% inr 49480000000 of its revenue for the 2013–14 fiscal year.[29] Cipla spent ₹517 crore (5.4% of their revenue) in the 2013–14 fiscal year on R&D activities.[29] The primary focus areas for R&D were development of new formulations, drug-delivery systems, and APIs. Cipla also cooperates with other enterprises in areas such as consulting, commissioning, engineering, project appraisal, quality control, know-how transfer, support, and plant supply.
Listings and shareholding
The equity shares of Cipla are listed on the Bombay Stock Exchange,[30] where it is a constituent of the BSE SENSEX index,[31] and the National Stock Exchange of India,[32] where it is a constituent of the CNX Nifty.[33] Its Global Depository Receipts (GDRs) are listed on the Luxembourg Stock Exchange.[29]
As of December 31, 2022, the promoter group, Y. K. Hamied and his family, held around 33.61% equity shares in Cipla. Individual shareholders hold approximately 14.72% of its shares. SBI Mutual Fund, LIC etc. are the largest non-promoter shareholders in the Company.[34] In January 2024, Samina Hamied resigned from her position as the Executive Vice Chairperson of Cipla. She continued to serve the company as a non-executive director subject to rotational retirement.
Awards and recognitions
- In 1980, Cipla won Chemexcil Award for Excellence for exports.[36]
- In 2006, Cipla won Dun & Bradstreet American Express Corporate Awards.[37]
- In 2007, Forbes included Cipla in the 200 'Best under a billion' list of best small Asian companies.[38]
- In 2012, Cipla received the Thomson Reuters India Innovation Award.[39]
- In 2015, Cipla stood third in the India's Most Reputed Brands (Pharmaceutical) list,[40] in a study conducted by BlueBytes,[41] a Media Analytics firm in association with TRA Research,[42] a brand insights organization (both part of the Comniscient Group).
Criticism
Emergency contraception
In August 2007, Cipla launched an emergency contraception drug "i-pill" sold over the counter,.[43] The drug sparked controversy as it was available without prescription and contained a large amount of API per dosage.[44][45]
Generic drugs
In the late 1960s, Cipla began manufacturing a new, patented drug, propranolol, without the permission of the drug's patent holder, Imperial Chemical Industries; a protest was filed with the Indian government. The CEO of Cipla pressured the government of Indira Gandhi to change India's patent laws to eliminate patents that directly covered drugs, and instead to allow only patents that covered methods to make drugs[46] so that Cipla could produce low-priced generic drugs. Since then, Cipla has also produced a low-cost drug to treat HIV, and expanded operations into several developing countries.[47] The changes made led to criticism of both India's patent laws and Cipla.[48] India reinstated patents on drugs in 2005.[46]
See also
- Pharmaceutical industry in India
- Generic drug
- List of pharmaceutical companies
External links
References
- Annual Report 2023-24 retrieved 24 May 2025^
- Q4 & FY25 results Cipla, retrieved 24 May 2025^
- Audited Financial Results (Standalone and Consolidated) for year ended 31st March 2025 Cipla, retrieved 24 May 2025^
- Cipla betting big on digitisation and emerging segments The Economic Times, retrieved 6 December 2022^
- Cipla betting big on digitisation and emerging segments Financial Express, retrieved 6 December 2022^
- About us - History Cipla Limited, retrieved 3 November 2014^
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- Katherine Eban. Bottle of Lies HarperCollins, 2019^
- PTI Dec 22. Indian pharma sector set for 'volume to value leadership' journey in 2023 The Economic Times, 2022-12-22, retrieved 2023-08-05^
- Introducing IPA- Indian Pharmaceutical Alliance IPA, Indian Pharmaceutical Alliance, retrieved 2023-08-05^
- Epic saga of Cipla: How a swadeshi Robin Hood took on Big Pharma of the West The Economic Times, 2023-08-05, retrieved 2023-08-05^
- Lohit Jawani. Cipla completes acquisition of South Africa's Cipla Medpro VC Circle, 16 July 2013, retrieved 8 September 2016^
- Delists from JSE Business Day Live, 2013, retrieved 13 July 2013^
- Enaleni Pharmaceuticals Limited Prospectus 2005 Morningstar, retrieved 8 September 2016^
- Tenu Avafia, Jonathan Berger, Trudi Hartzenberg. The ability of select sub-Saharan African countries to utilise TRIPs Flexibilities and Competition Law to ensure a sustainable supply of essential medicines: A study of producing and importing countries WHO, 2006^
- Tamar Kahn. South Africa: Enaleni Takes Name of Its Unit Cipla-Medpro All Africa, 10 September 2008^
- Vishnu Priyan. Cipla to bolster OTC portfolio with acquisition of Actor Pharma Pharmaceutical Technology, 2023-09-05, retrieved 2023-09-05^
- LISA JARVIS. Mylan Will Buy Most of Matrix Chemical & Engineering News Archive, 2006-09-04^
- Cipla's History Cipla South Africa, n.d., retrieved 2022-05-16^
- Cipla to acquire Ivia Beaute's cosmetics, personal care biz for Rs 130 cr Business Standard India, 16 April 2024, retrieved 21 April 2024^
- cipla ltd (CIPLA:Natl India) Business Week, retrieved 7 November 2013^
- Annual Report FY 2022-23 Cipla.com, Cipla, 15 July 2014, retrieved October 11, 2023^
- AIDS Healthcare Foundation Campaign Challenges Cipla Over Drug Pricing in India PR Newswire, 8 August 2007, retrieved 4 November 2013^
- India gives Hetero Labs and Cipla approval to make Gilead's COVID-19 drug Reuters, 21 June 2020, retrieved 7 August 2020^
- Coronavirus drug: Cipla launches Cipremi's, claims it is the cheapest Remdesivir The Financial Express, 9 July 2020, retrieved 7 August 2020^
- Coronavirus drug: Cipla ramps up production of antiviral remdesivir amid demand spurt businesstoday.in^
- Corporate Information: At a Glance Cipla, retrieved 6 July 2019^
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- Latest CIPLA Shareholding Pattern Equitymaster, retrieved 2023-01-25^
- Company Profile - Cipla Limited IndiaInfoline.com, retrieved 3 November 2013^
- Pharmaceutical sector award Dun & Bradstreet, 10 September 2006, retrieved 3 November 2013^
- Asian Paints, Cipla in Forbes list Economic Times, 17 November 2005, retrieved 3 November 2013^
- DBT, Cipla get Thomson Reuters India innovation awards retrieved 24 November 2012^
- "Lupin, Sun Pharma and Cipla amongst tops most reputed pharma brand list". The Economic Times. timesofindia.com. 17 August 2016. Retrieved 6 July 2019.^
- Home bluebytes.info, retrieved 7 August 2022^
- Home trustadvisory.info, retrieved 7 August 2022^
- Cipla rises on morning-after pill Hindustan Times, 5 October 2007, retrieved 3 November 2013^
- Cipla Launches i-pill Financial Express, retrieved 3 November 2013^
- 'i-pill' by Cipla draws criticism from experts Financial Express, 27 October 2007, retrieved 3 November 2013^
- The Treasure of Mumbai Wired Magazine, December 2006, retrieved 4 November 2013^
- Heart-warming story of the Hamieds, who set up CIPLA and have been saving lives National Herald, April 2020, retrieved 12 April 2020^
- Indian Generic Drug Maker Targets Sad Americans biohealthinvestor.com, 3 January 2007, retrieved 4 November 2013^